Optical Stimulation in Peripheral Nerves for Select Rhizotomy Procedures

Vanderbilt University

Status: Completed

Conditions: Spasticity

Treatments: Procedure: Rhizotomy for children with spasticity

Study type: Observational

Funder types: Other

Identifiers

NCT00575536

050822

Details and patient eligibility

About

The purpose of this study is to determine the safe and effective levels of optical stimulation in peripheral nerves of humans otherwise undergoing nerve lesioning in surgery.

Full description

The purpose of this study is to determine the safe and effective levels of optical stimulation in peripheral nerves of humans otherwise undergoing nerve lesioning in surgery, namely children undergoing selective rhizotomy for treatment of medically refractory spasticity.

Enrollment: 19 patients

Sex: All

Ages: 3 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children over the age of 3 and younger than 17 years
• Children who have failed appropriate medical therapy and are recommended for selective rhizotomy to treat spasticity by the pediatric neurosurgeon
• Children who would normally undergo electrodiagnostic testing including EMG monitoring for physiologic testing during surgery
• Surgery must be performed at the Vanderbilt University Children's Hospital

Exclusion criteria

• Patients in which a segment of the nerve (up to 2cm) cannot likely be identified at the time of surgery as determined by the pediatric neurosurgeon
• Children not undergoing routine selective rhizotomy for medically refractory spasticity as determined by the pediatric neurosurgeon
• Children who are medically unstable to tolerate an additional 20 minutes of experimental testing during the surgery
• Women who are pregnant will be excluded from this study

Trial design

19 participants in 1 patient group

Rhizotomy for children with spasticity

Description:

Children with spasticity needing Rhizotomy surgery

Treatment:

Procedure: Rhizotomy for children with spasticity