Optimal Antiplatelet Therapy for Chinese Patients With Coronary Artery Disease (OPT-CAD)

Shenyang Northern Hospital

Status: Completed

Conditions: Coronary Artery Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01735305

SYNH-20121113

Details and patient eligibility

About

Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years old who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were physician discretion.

Full description

Antiplatelet therapy is the cornerstone for the prevention of atherothrombosis in patients with coronary artery disease (CAD). However, the efficacy and safety of antiplatelet therapy are varied due to ethnic and/or individual variability. The aim of the OPT-CAD study was to demonstrate contemporary status and outcomes of antiplatelet therapy in Chinese CAD patients, and to explore predictors of ischemic or bleeding events in such cohort.Patients above 18 years who were diagnosed as CAD and received antiplatelet therapy were prospectively enrolled in this national wide, non-intervention registry. All medications and laboratory tests were at physician discretion.

Enrollment: 14,032 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Clinical diagnosis of coronary heart disease
2. Age >= 18 years old
3. receiving any antiplatelet agents
4. Informed written consent signed

Exclusion criteria

1. With severe disease and life expectancy for 6 months or less
2. Difficult to attain follow-up situations judged by researchers (travel, speech or mental disorder, etc.)
3. Taking part in an interventional clinical research

Trial design

14,032 participants in 1 patient group

Antiplatelet therapy

Description:

patients with coronary artery disease receiving any antiplatelet therapy, without any intervention by the investigators.