Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI (Lipid-PCI)

Samsung Medical Center

Status: Completed

Conditions: Coronary Artery Disease; Hyperlipidemias

Treatments: Drug: LDL reduction therapy

Study type: Observational

Funder types: Other

Identifiers

NCT06338956

Lipid-PCI

Details and patient eligibility

About

For the management of low-density lipoprotein-cholesterol (LDL-C), some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in LDL-C levels. High-intensity or maximally tolerated intensity can be maintained without a target goal. However, the European guideline recommends less than 55 mg/dL of LDL-C after PCI.

Full description

To investigate the Optimal Attained LDL-C Levels in Patients Who Achieved ≥50% LDL-C Reduction After PCI.

Enrollment: 135,877 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients receiving PCI with health check up before and after PCI within 3 years

Exclusion criteria

• Patients receiving statin before PCI
• Patients with liver cirrhosis
• Patients with cancer
• Patients without prescription of statin
• Patients with LDL-C <55 mg/dL before PCI

Trial design

135,877 participants in 2 patient groups

>=50% LDL-C reduction

Description:

LDL-C reduction \>=50% Further divided by LDL \<55mg/dL 55\< LDL \< 70 mg/dL LDL \> 70 mg/dL

Treatment:

Drug: LDL reduction therapy

<50% LDL-C reduction

Description:

LDL-C reduction \<50%

Treatment:

Drug: LDL reduction therapy