Optimal Exercise Training and Nutrition Supplementation in Older Men

McMaster University

Status: Completed

Conditions: Aging

Treatments: Dietary Supplement: Supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT02281331

REB 14-677

Details and patient eligibility

About

As we age we tend to lose muscle mass and strength. These losses contribute to the increased incidence of falls and fractures, metabolic diseases such as type 2 diabetes, loss of independence and reduced quality of life in the elderly. As the number of seniors increases worldwide, it is becoming more and more important to develop strategies to counteract this loss of muscle mass and strength, and promote healthy aging. Fortunately, relatively simple lifestyle modifications are the most potent defense strategies. Exercises such as weight lifting and high-intensity interval exercise (HIIT), which consists of short, repeated bouts of vigorous aerobic exercise interspersed with period of rest, are the most effective in promoting gains in muscle mass and strength. Additionally, components of foods like whey (a protein found in milk), creatine (found in meat), calcium and vitamin D have been shown to independently increase strength. In this study, we are looking to determine how much we can increase muscle strength in older men who are put on an 12 week exercise training program that combines weight lifting and HIIT, and who consume a daily supplement that contains whey protein, creatine, calcium and vitamin D.

Full description

Please see other documentation.

Enrollment: 50 patients

Sex: Male

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sedentary (no participation in a structured exercise training program in past 6 months)
• BMI between 18.5-30.0 kg/m2
• Weight stable for past 6 months
• Normal resting blood pressure, or stage I hypertension

Exclusion criteria

• Smoking
• Use of simvastatin or atorvastatin
• Use of non-steroidal anti-inflammatory drugs
• Injuries that prevent safe-participation in an exercise training program
• Prescription blood thinners
• Diabetes or other metabolic disorders
• Cardiac or gastro-intestinal problems
• Infectious disease or cancer

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

Supplement

Active Comparator group

Description:

Each day, participants in this group will receive a supplement that provides a total of protein, creatine monohydrate, calcium, vitamin D and carbohydrate. This supplement will be provided to participants in beverage format, twice daily.

Treatment:

Dietary Supplement: Supplement

Placebo

Placebo Comparator group

Description:

The placebo will provide participants with maltodextrin (carbohydrate) and sucrose.

Treatment:

Dietary Supplement: Supplement