Optimal Number of Pleural Biopsies During Pleuroscopy (OPTIBIOP)

Mount Sinai Health System

Status: Completed

Conditions: Pleural Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT06897878

STUDY-24-01325

Details and patient eligibility

About

A single-center, non-randomized, prospective observational, pilot study designed to determine what is the optimal number of pleural biopsies to take during pleuroscopy.

Full description

After enrollment, participants will undergo pleural biopsies via pleuroscopy. Specimens will be divided into three aliquots (1-3, 4-6, 7-10), which will be sent to pathology. A designated pathologist will evaluate the specimens in each aliquot to determine the number of biopsies required to reach a diagnosis and to obtain sufficient material for biomarker testing (when needed), and determine whether analysis of further aliquots is needed.

Enrollment: 104 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients who require pleuroscopies will be enrolled to the study.
• Age ≥ 18

Exclusion criteria

- Inability to provide informed consent

Trial design

104 participants in 1 patient group

Pleural biopsy

Description:

All consecutive patients referred for a pleuroscopy.