Optimal Strategy for Side Branch Stenting in Coronary Bifurcation Lesion

Samsung Medical Center

Status

Completed

Conditions

Coronary Artery Disease

Treatments

Procedure: Conservative strategy

Procedure: Aggressive strategy

Study type

Interventional

Funder types

Other

Identifiers

NCT00794014

2007-08-073

Details and patient eligibility

About

The purpose of this study is to establish the optimal strategy for side branch stenting in coronary bifurcation lesion.

Full description

The purpose of this study is to evaluate the relative efficacy and safety of conservative strategy compared to aggressive strategy for side branch stenting in coronary bifurcation lesion.

Enrollment

258 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Parent vessel diameter stenosis > 75%
Parent vessel diameter stenosis 50% - 75% with angina and/or objective evidence of ischemia in the non-invasive stress test
The reference diameter of both branches more than 2.3 mm by visual estimation

Exclusion criteria

Cardiogenic shock
ST-elevation myocardial infarction within 48 hours of symptom onset
Left ventricular dysfunction (echocardiographic left ventricular ejection fraction < 25%)
Graft vessels
Patients who have to receive clopidogrel due to other conditions
Patients who have to receive warfarin, cilostazol or other antiplatelet therapy
Hypersensitivity to clopidogrel or aspirin
Expectant survival less than 1 year
Women who plan to become pregnant
Patients with bleeding diathesis (coagulopathy, thrombocytopenia or platelet dysfunction, Gastrointestinal or genitourinary bleeding within the prior 3 months)
Patients who are actively participating in another drug or device investigational study, which have not completed the primary endpoint follow-up period.