Optimization of Oocyte Warming Protocols (OVOfast)

San Donato Group (GSD)

Status: Active, not recruiting

Conditions: Oocyte Cryopreservation

Treatments: Other: Thawing protocol; Other: thawing protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT07105891

OVOfast

Details and patient eligibility

About

This is a retrospective study with a sibling design comparing new oocyte thawing protocols (rapid and ultra-rapid) with the traditional method

Enrollment: 399 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Vitrified oocytes from the Centro Scienze della Natalità, IRCCS San Raffaele Hospital
• Patients who explicitly consented to the disposal of their stored gametes and authorized their use for research purposes through the informed consent process
• Oocytes cryopreserved using the vitrification technique
• Patients age 20-39 yo

Exclusion criteria

• All oocytes cryopreserved using the slow freezing technique
• Oocytes from patients older than 40 years

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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399 participants in 3 patient groups

Standard

Other group

Description:

Standard thawing

Treatment:

Other: Thawing protocol

Fast

Other group

Description:

Fast thawing

Treatment:

Other: thawing protocol

Other: thawing protocol

Ultrafast

Other group

Description:

Ultrafast thawing

Treatment:

Other: thawing protocol

Other: thawing protocol