Optimization of PEEP for Alveolar Recruitment in ARDS (OPERA)

Hopital of Melun

Status: Completed

Conditions: ARDS

Treatments: Device: esophageal pressure mesurement

Study type: Observational

Funder types: Other

Identifiers

NCT01949272

OPERA (Other Identifier)

Details and patient eligibility

About

Actual setting of PEEP in ARDS is based on tables linked to FiO2, or respiratory system plateau pressure (e.g EXPRESS Study) or set regarding esophageal pressure mesurement and transpulmonary pressure calculation. Opera study should confirm if a setting approach based on esophageal pressure is helpfull for any ARDS patient in ICU without deleterious side-effect.

Enrollment: 22 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ARDS Stades 2 and 3 with invasive ventilation (EXPRESS settings) within 3 to 12 hours

Exclusion criteria

• less 18 years, pregnancy, intracardiac shunt, esophageal catheter cons-indicated

Trial design

22 participants in 1 patient group

ARDS

Description:

ARDS patients achieving stades II and III of Berlin 2011 Classification

Treatment:

Device: esophageal pressure mesurement