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Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals

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Philipps University

Status

Completed

Conditions

Spider Fear
Arachnophobia

Treatments

Behavioral: Exposure
Behavioral: occasional aversive imagination

Study type

Interventional

Funder types

Other

Identifiers

NCT05424250
OPEX_SPIDER

Details and patient eligibility

About

The effectiveness of an optimized extinction training is investigated in spider-fearful individuals. Participants will undergo a one-session standardized extinction training, either with or without occasional metal imagination of most feared apprehension towards spiders. The effectiveness of the training is measured by symptom improvement according to subjective ratings and behavioural avoidance tests one week later.

Full description

The present study aims to investigate the applicability of an optimized exposure training using imagination. Exposure training is an effective approach to the treatment of various anxiety disorders. However, there are a significant number of patients who do not benefit or who develop anxiety following successful treatment. The process of extinction underlying exposure is the focus of current research on optimizing exposure. In this regard, one promising approach for improving extinction learning involves the occasional presentation of fear-generating stimuli (unconditioned stimuli [US]; often an electrical stimulus in experimental studies) during extinction (occasional reinforced extinction, ORE). Previous experimental studies provide preliminary evidence for a less pronounced return of fear after extinction training with occasional presentation of the US. In clinical practice, this strategy is recommended to optimize extinction learning in the treatment of individuals with anxiety. However, the transfer of the procedure used (real presentation of an unconditioned stimulus) into clinical practice seems difficult to realize. One way to facilitate the transfer of the ORE approach into clinical practice could be the use of vivid imagination of a personally relevant fear-generating situation during extinction training/exposure (e.g., patients' central concerns). Therefore, the aim of the present study is to examine the applicability of ORE using imagination. In this context, a standardized extinction training either with or without mental imagination of a personally relevant fear situation (e.g., central concern of the consequences when confronted with spiders) will be performed in individuals with spider-fearful individuals. The approach used for individuals with spider fear is well established and has been successfully implemented in previous studies by instructed trainers (e.g., individuals with a bachelor's degree in psychology). The aim of this randomized controlled trial in healthy individuals with increased fear of spiders is to investigate whether optimized extinction training (extinction training + imagination) is more effective in reducing fear of spiders in the long term compared to standard extinction training.

Enrollment

67 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Elevated score on Spider Phobia Questionnaire (SPQ) > 17

Exclusion criteria

  • Severe allergies to bees/spiders/insects
  • current psychotherapeutic/psychiatric treatment
  • past psychotherapeutic/psychiatric treatment due to anxiety problems
  • current or past psychotic symptoms
  • current suicidal intent
  • experience with exposure-based treatment
  • current psychopharmacological medication
  • severe cardiovascular, respiratory or neurological diseases

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

67 participants in 2 patient groups

Exposure + occasional aversive imagination
Experimental group
Description:
repeated imaginations of the participants' most feared apprehension during extinction training with seven standardized exposure steps
Treatment:
Behavioral: occasional aversive imagination
Behavioral: Exposure
Exposure
Active Comparator group
Description:
Standard extinction training with seven standardized exposure steps
Treatment:
Behavioral: Exposure

Trial contacts and locations

1

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Central trial contact

Christiane A Pané-Farré, PhD; Christoph Benke, PhD

Data sourced from clinicaltrials.gov

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