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Optimizing Hemodialysis: How Low Dialysate Flow Alters Adequacy and Patient Recovery.

A

Alexandria University

Status

Completed

Conditions

End Stage Kidney Disease (ESRD)

Treatments

Other: lower dialysate flow rate ( 300ml/min). then testing its effect on hemodialysis adequacy

Study type

Interventional

Funder types

Other

Identifiers

NCT07360769
0108861

Details and patient eligibility

About

The goal of this clinical trial is to detect if lower dialysate flow rate can affect hemodialysis adequacy , dialysis recovery time and patients quality of life.

The main questions it aims to answer are:

does low dialysate flow affect hemodialysis adequacy? does green dialysis achievable without affecting hemodialysis adequacy? Researchers will compare hemodialysis session of high dialysate flow to that with low dialysate flow.

Participants will:

underwent hemodialysis for a week with low dialysate flow and another week with high dialysate flow.

Enrollment

80 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • ESKD patients more than or equal 18 years old, on maintenance HD thrice weekly for more than three months and each session lasts for 4 hours.
  • All patients will receive HD via an arterio-venous fistula.
  • All patients will receive HD via the same type of HD machine and the blood pump will be set at 300ml/min.
  • All patients will receive the same type of HD membranes and every effort will be made to achieve the dry weight of the patients.

Exclusion Criteria :

  • Critically ill and hospitalized ESKD patients.
  • Mentally disabled patients.
  • Patients with terminal malignancy or receiving chemotherapy.
  • Patients receiving immune suppression treatment.

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

80 participants in 1 patient group

ESKD patients
Active Comparator group
Treatment:
Other: lower dialysate flow rate ( 300ml/min). then testing its effect on hemodialysis adequacy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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