Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures

The University of Texas System (UT)

Status: Begins enrollment this month

Conditions: Airway Disorder

Treatments: Device: High flow; Device: Low Flow

Study type: Interventional

Funder types: Other

Identifiers

NCT06947902

HSC-MS-25-0028

Details and patient eligibility

About

The purpose of this study is to investigate which flow rate (higher versus lower) is most effective at increasing apneic time and preventing greater than 5% drop in desaturation, as well as assessing transcutaneous carbon dioxide (CO2) levels during airway procedures in children

Enrollment: 80 estimated patients

Sex: All

Ages: Under 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• undergoing laryngoscopy and bronchoscopy procedures at Children's Memorial Hermann Hospital (CMHH)
• weight greater than or equal to 5 kilograms and using flow rates between 5 to 45 liters per minute (BTPS)

Exclusion criteria

• Emergency type cases, tracheostomy patients, unrepaired cyanotic heart disease, nasal deformity/choanal atresia, or cautery/laser type procedures

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

High flow

Experimental group

Treatment:

Device: High flow

Low Flow

Experimental group

Treatment:

Device: Low Flow