Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management (BIOSUPORT)

University of Limoges (UL)

Status

Enrolling

Conditions

Organ Transplantation

Treatments

Other: blood and urine samples

Study type

Interventional

Funder types

Other

Identifiers

NCT03997253

87RI18-0027

Details and patient eligibility

About

Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs. Despite undeniable success in the short term, due to major advances in surgery, medicine and research, transplant recipients continue to face the risk of chronic rejection and long-term complications.

The University Hospital Federation "FHU SUPORT" was created to optimize the chances of success of the organ transplant and improve the quality of life of the transplanted patient. FHU SUPORT 's ambition is based on a translational strategy that presents two priority areas:

Axis 1: Optimization, evaluation, conditioning of the donor, graft, recipient Axis 2: Personalized follow-up of the transplanted patient in the short and long term Identifying factors for long-term graft and patient survival through translational research from a common cohort and biological collection will predict transplant rejection, prolong graft function, or improve the patient's care.

Enrollment

430 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male or female over 18 (no age limit)
affiliated to a social security organization
Recipient (s) of a kidney, liver or heart transplant
followed by at least one of the FHU SUPORT centers (Tours, Poitiers, Limoges, Rennes)
having given informed consent to participate in the cohort.

Exclusion criteria