Optimizing Meal and Snack Timing to Promote Health (S43)

Purdue University

Status: Completed

Conditions: Dietary Modification

Treatments: Other: 10 g protein breakfast; Dietary Supplement: 10 + 20 g protein consumption; Other: 30 g protein breakfast

Study type: Interventional

Funder types: Other

Identifiers

NCT02506218

1501015661

Details and patient eligibility

About

This study will be conducted using standardized techniques to collect blood samples via an acute, randomized, cross-over design. Subjects will be provided all of their meals the day prior to testing and participate in 3 testing days with a minimum of 1 week break between testing days and a maximum time commitment of 7 weeks. A trained phlebotomist will place a catheter and collect blood samples from an antecubital vein using sterile techniques.

Enrollment: 12 patients

Sex: All

Ages: 25 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

25-39 years old

• BMI between 22-37 kg/m2
• Weight stable (± 4.5 kg) for the previous 3 months
• Not currently (or within the past 6 months) following a vigorous exercise regimen or weight loss program
• No acute illness
• Not smoking
• Not diabetic
• Not pregnant or planning pregnancy in the next 3 months
• Lactose tolerant
• Willing to limit purposeful activity for 48 hours prior to each testing day
• Willing to consume study foods and beverages.

Exclusion criteria

• <25 or >39 years old, BMI <22 or >37 kg/m2
• Currently (or within the past 6 months) following a vigorous exercise regimen greater than -3 - 45 minute exercise sessions per week
• Currently following a weight loss program where subject has lost greater than 4.5 kg
• Acute illness
• Smoking
• Diabetic
• Pregnant or planning pregnancy in the next 3 months
• Lactose intolerant
• Unwilling to consume study foods and beverages
• Peri and post-menopausal women.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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12 participants in 3 patient groups

10 + 20 g protein consumption

Experimental group

Description:

10 g breakfast followed by the consumption of a 20g whey protein shake

Treatment:

Dietary Supplement: 10 + 20 g protein consumption

30 g protein breakfast

Active Comparator group

Treatment:

Other: 30 g protein breakfast

10 g protein breakfast

Active Comparator group

Treatment:

Other: 10 g protein breakfast