Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery

Ain Shams University

Status: Completed

Conditions: Postoperative Pain

Treatments: Other: Bupivacain; Other: Bupivacaine and ketamine; Other: Bupivacaine and transdermal fentanyl patch

Study type: Interventional

Funder types: Other

Identifiers

NCT06007378

FMASU MS 416 / 2023

Details and patient eligibility

About

Erector spinae plane block (ESPB) is a novel regional block technique that was proven to have superior outcomes in relieving postoperative pain in colorectal surgeries.Ketamine enhances the impact of local anaesthetics by reducing the duration and extent of motor block while shortening the onset of sensory and motor block.Transdermal Fentanyl Patch (TFP) was better than transdermal buprenorphine in postoperative analgesia following abdominal surgeries.

Enrollment: 120 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing laparoscopic colorectal surgery.
• American Society of Anesthesiologists (ASA) physical status I or II.

Exclusion criteria

• Known allergy to one of the study medications.
• Skin infections at the site of the needle puncture.
• Hepatic, renal or cardiac dysfunction.
• Patients diagnosed with obstructive sleep apnoea

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 3 patient groups

Bupivacaine and ketamine

Other group

Treatment:

Other: Bupivacaine and ketamine

Bupivacaine and transdermal fentanyl patch

Other group

Treatment:

Other: Bupivacaine and transdermal fentanyl patch

Bupivacaine

Other group

Treatment:

Other: Bupivacain