Optimizing Resuscitation After Cardiac Arrest in the Community

Shaare Zedek Medical Center

Status: Unknown

Conditions: Cardiopulmonary Arrest Outcome

Study type: Observational

Funder types: Other

Identifiers

NCT00998140

NIHPR 08/90/a

Details and patient eligibility

About

Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs.

Study hypotheses:

1. Subpopulations for whom intervention is futile/counter-productive are identifiable
2. Substantial waste of resources can be avoided
3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

Enrollment: 1,600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Exclusion criteria

• Patients with do-not-resuscitate orders or an advance directive to that effect.