Optimum Menstrual Cycle Time for Endometrioma Excision

Acibadem University

Status: Completed

Conditions: Endometriosis; Endometrioma

Treatments: Procedure: laparoscopic endometrioma cyst excision

Study type: Observational

Funder types: Other

Identifiers

NCT03484546

AcibademGynecology

Details and patient eligibility

About

This study evaluates the optimum day of menstrual period for the excision of endometriomas to minimize the damage of surgery to normal ovarian tissue. Patients will be grouped as follicular, ovulatory and luteal according to menstrual days. Ovarian damage will be evaluated with both pathologic examination and anti-mullerian hormone levels before and after the surgery.

Full description

Endometriosis is a common gynecologic disease seen in about 10% of women in reproductive age. The most common site of endometriosis is overt. Cystic formation of ovarian endometriosis is called endometrioma (chocolate cyst). Definitive treatment of endometriomas is excision by laparoscopy. The disadvantage of this surgery is the removal of some of the normal ovarian follicles within cystectomy material. This procedure can damage the ovarian reserves with the treatment of endometriomas, which are already the cause of infertility, and lead to the conditions such as infertility or early menopause. It has been understood that the ovarian reserves of the patients who underwent endometrioma cystectomy with the decrease of the Anti-Mullerian Hormone values, which is an over reserve parameter.

Enrollment: 60 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 4 to 10 cm unilateral ovarian endometrioma
• having clinically indication of laparoscopic ovarian endometrioma excision

Exclusion criteria

• prior gynecologic surgery
• prior abdominal surgery
• additional operation in the same session
• having the diagnosis of premature ovarian failure or ovarian insufficiency
• having any diagnosis of malignancy
• having diagnosis of a non-gynecologic chronicle disease

Trial design

60 participants in 3 patient groups

folicular

Description:

Women who will undergo endometrioma cystectomy in her follicular phase of menstrual period.

Treatment:

Procedure: laparoscopic endometrioma cyst excision

ovulatory

Description:

Women who will undergo endometrioma cystectomy in her ovulatory phase (12-14th day of mestrual period cycle for women regular period) of menstrual cycle.

Treatment:

Procedure: laparoscopic endometrioma cyst excision

luteal

Description:

Women who will undergo endometrioma cystectomy in her luteal phase of menstrual period.

Treatment:

Procedure: laparoscopic endometrioma cyst excision