Oral Caffeine and Spinal-Induced Hypotension

Cairo University (CU)

Status: Completed

Conditions: Caffeine; Spinal Hypotension

Treatments: Drug: Placebo; Drug: Caffeine (200 mg)

Study type: Interventional

Funder types: Other

Identifiers

NCT07076654

Caffeine and hypotension

Details and patient eligibility

About

Hypotension after spinal anesthesia is critical. Thus several interventions have been proposed to mitigate such effect.

Full description

Hypotension is a critical issue related to spinal anesthesia during cesarean delivery. Researchers of this study aimed to evaluate the impact of preoperative oral caffeine on the incidence of spinal hypotension during cesarean delivery.

Enrollment: 90 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• full term pregnant
• undergoing elective cesarean delivery

Exclusion criteria

• patient refusal
• baseline systolic pressure < 100 mmHg
• contraindication to spinal anesthesia
• allergy to caffeine

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups, including a placebo group

Caffeine

Active Comparator group

Description:

Patients will receive oral caffeine 200 mg before spinal anesthesia

Treatment:

Drug: Caffeine (200 mg)

Control group

Placebo Comparator group

Description:

Will receive placebo before spinal anesthesia

Treatment:

Drug: Placebo