Oral Care Protocol for Preventing Ventilator- Associated Pneumonia (VAP)

Mackay Memorial Hospital

Status and phase: Completed; Early Phase 1

Conditions: Pneumonia

Treatments: Other: mimic protocol; Other: standardized oral care protocol - electronic toothbrush

Study type: Interventional

Funder types: Other

Identifiers

NCT00604916

MMH-I-S-402

Details and patient eligibility

About

The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms. Research indicates that the Gram-Negative Bacteria grows in upper air way and trachea rapidly during the initial 2-4 hospital days and the dental plague also increased dramatically at the first 5 days. About 50% cases with prolonged intubation experienced temporal swallowing disorders and majority of them recovered 7 days post weaning. Some evidence exist suggesting that oral care could reduce bacterial flora, prevent aspiration, and subsequently decrease the incidence of ventilation-associated pneumonia for this group of high risk patients.

This study aims to evaluate the effectiveness of a standardized oral care protocol in improving oral hygiene and reducing the incidence of pneumonia on a sample of surgical patients at intensive care unit.

Enrollment: 53 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients newly admitted to SICU who were under ventilator support for 48~72 hours

Exclusion criteria

• With pneumonia present

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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53 participants in 2 patient groups, including a placebo group

E

Experimental group

Description:

received a 7 day standardized oral care protocol

Treatment:

Other: standardized oral care protocol - electronic toothbrush

C

Placebo Comparator group

Description:

received a 7 day mimic protocol

Treatment:

Other: mimic protocol