Oral Care to Prevent Ventilator-associated Pneumonia

Ataturk University

Status: Completed

Conditions: Ventilators, Mechanical; Oral Hygiene, Oral Health

Treatments: Combination Product: One group received standard oral care.; Combination Product: It was applied to the other group by aspiration.

Study type: Interventional

Funder types: Other

Identifiers

NCT05161962

AtaturkU-001

Details and patient eligibility

About

This study was conducted to investigate the effect of oral care given by two different methods on the development of ventilator-associated pneumonia in patients connected to mechanical ventilators.

Full description

The universe of this research, which was designed as a semi-experimental study, is composed of patients connected to the mechanical ventilator lying in Atatürk University Training and Research Hospital Anesthesia and Reanimation Intensive Care Unit between September 2019 and February 2020. A total of 57 patients, 29 method-1, 28 method-2 groups, met the inclusion criteria of the study. In the data collection phase, 'Patient Identifier Information Form', 'Patient Monitoring Form', 'Oral Assessment Scale' and 'Tracheal Aspirate Culture Result Form' were used. In the evaluation of the data, number and percentage distributions, Kruskal Wallis, Mann Withney-U, Wilcoxon Analysis, Chi-Square test were used.

Enrollment: 57 patients

Sex: Female

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:• Patients on mechanical ventilator who have been in intensive care for at least 48 hours

• Male and female patients over the age of 18
• Patients without thrombocytopenia, leukopenia and oral stomatitis, aphthae, candiasis, gingivitis
• Patients whose respiratory support is provided by a mechanical ventilator
• Patients who are considered to be able to provide mechanical ventilator support for 7 days
• Patients without any respiratory-related infectious pathogens
• Obtaining informed consent from the patient if he/she can give consent or from his/her guardian if he/she is unable to give consent.
• It was determined as patients who did not undergo any intraoral surgical intervention.

Exclusion Criteria: patients with pneumonia Patients younger than 18 years

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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57 participants in 2 patient groups, including a placebo group

One group received standard oral care.

Experimental group

Treatment:

Combination Product: It was applied to the other group by aspiration.

Combination Product: One group received standard oral care.

It was applied to the other group by aspiration.

Placebo Comparator group

Treatment:

Combination Product: It was applied to the other group by aspiration.

Combination Product: One group received standard oral care.