Oral Health, Microbial Burden and COVID-19 (ORACLE)

Eastman Dental Insitute and Hospital

Status: Unknown

Conditions: Periodontitis; Covid19

Treatments: Other: Swab

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT04668911

283766 (Other Identifier)

EDGE 132868

Details and patient eligibility

About

An observational study of patients with COVID-19 confirmed cases (with various degrees of severity) and controls.

Oral and nasal swabs will be taken from 150 patients (50 with mild form and 50 with severe form of COVID-19 with or without mechanical ventilation, 50 healthy controls).

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Must provide written informed consent
2. Subjects have to be tested (PCR) positive or negative for SARS-CoV2 infection
3. Must be able to provide oral and nasal swabbing within 48 hours of polymerise chain reaction (PCR) test results

Exclusion criteria

a. Under the age of 18 years old

Trial design

150 participants in 3 patient groups

Controls tested PCR (-) for COVID-19

Treatment:

Other: Swab

Tested PCR (+) for COVID-19, Mild - not admitted to the hospital

Treatment:

Other: Swab

Tested PCR (+) for COVID-19, Severe - admitted to ICU (Intensive Care Unit)

Treatment:

Other: Swab