Oral Morphine Versus Ibuprofen

Naveen Poonai

Status: Completed

Conditions: Analgesia Post Fracture; Upper Extremity Fractures

Treatments: Drug: Ibuprofen; Drug: Oral morphine

Study type: Interventional

Funder types: Other

Identifiers

NCT01690780

R-11-340

18091 (Other Identifier)

Details and patient eligibility

About

Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24 hours following discharge from the emergency department. Pain will be assessed using the self-report Faces pain scale revised (FPS-R). We hypothesize that oral morphine will result in greater pain relief than ibuprofen.

Enrollment: 183 patients

Sex: All

Ages: 5 to 17 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Exclusion Criteria:

• patients with known hypersensitivity to either ibuprofen or morphine
• chronic users of NSAIDS or opioids
• fractures requiring operative management
• associated injuries requiring analgesia
• poor English fluency
• pregnancy

Inclusion Criteria:

• All patients aged 5 to 17 years with a non-operative forearm or distal radius fracture

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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183 participants in 2 patient groups

Ibuprofen

Active Comparator group

Treatment:

Drug: Ibuprofen

Oral morphine

Experimental group

Treatment:

Drug: Oral morphine