Oral Morphine Versus Ketamine in Pain Management

Mbarara University of Science and Technology

Status and phase: Completed; Phase 3

Conditions: Pain, Procedural

Treatments: Drug: GROUP A; Drug: GROUP B

Study type: Interventional

Funder types: Other

Identifiers

NCT05163366

2021/ANDREW

Details and patient eligibility

About

The study will mainly focus on procedural pain management using oral morphine versus rectal ketamine during paediatric burn and wound dressing at Mbarara Regional Referral Hospital.

Full description

Subjects will be randomly assigned to one of the two treatment groups A and B. Guardians of patients who are scheduled for burn wound care will sign written consent pre- operatively about procedural pain management. Group A will receive rectal ketamine while those in Group B will receive only traditional standard of care protocols.

Enrollment: 44 patients

Sex: All

Ages: 6 months to 6 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pediatric patients between 6 months and 6-years old scheduled for a minimum of one procedure for burn wound dressing at the pediatric unit at Mbarara Regional Referral Hospital

Exclusion criteria

• Children with rectal or anal pathology,
• Refusal to assent to participate or parental or guardian refusal to consent in the study
• Children who require mechanical ventilation or already intubated in Intensive care unit
• Those allergic to Ketamine or its constituents

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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44 participants in 2 patient groups

GROUP A

Experimental group

Description:

Group A will receive rectal ketamine(Ket)

Treatment:

Drug: GROUP A

GROUP B

Active Comparator group

Description:

Group B will receive only traditional standard of care protocols.

Treatment:

Drug: GROUP B