Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

Integrative Skin Science and Research

Status

Enrolling

Conditions

Photoaging

Treatments

Dietary Supplement: Astaxanthin 6 mg daily

Dietary Supplement: Placebo

Study type

Interventional

Funder types

Industry

Other

Identifiers

NCT05882084

Asta_Skin_01

Details and patient eligibility

About

This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.

Enrollment

24 estimated patients

Sex

Female

Ages

30 to 55 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Females who are 30 to 55 years of age
Half of the women will have Fitzpatrick skin type 1-3 and the other half of the women will have Fitzpatrick skin type 4-6

Exclusion criteria

Individuals with a known allergy to astaxanthin or other carotenoids (such as zeaxanthin, lutein, lycopene).
Individuals who are unwilling to discontinue carotenoid supplementation for at least 1 month prior to enrollment
Individuals unwilling to restrict intake of foods like shrimp, salmon, mangos, carrots, and tomatoes during the study.
New supplementation within 4 weeks with tocopherol
Individuals who are unwilling to stay consistent with a facial cleansing regimen.
Those who are unwilling to discontinue topical hydroquinone, retinoid or benzoyl peroxide for 2 weeks prior to enrollment
Individuals who are pregnant or breastfeeding.
Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years