Oral Vitamin D Supplementation in Elderly Women

University of Helsinki

Status: Completed

Conditions: Optimal Vitamin D Administration

Treatments: Dietary Supplement: vitamin D twice daily; Dietary Supplement: Vitamin D3 oil three times in a year

Study type: Interventional

Funder types: Other

Identifiers

NCT00575835

77/2006

Details and patient eligibility

About

The aim of this study is to compare oral vitamin D supplementation administered in two different ways, namely either twice a day (800IU/d, 292000IU/y) or three times a year (97333IU every 4 months, 292000IU/y) in elderly women in combination with daily supplementation of calcium 1 gram. We will 1)compare the blood concentrations of 25 OH vitamin D in the two treatment groups amd monitor if a sufficient and safe concentration of 25OH D in blood can be maintained with these two treatments.2) Find out seasonal variation in vitamin D concentrations in these treatments. 3) Find out safety of these treatments

Enrollment: 40 patients

Sex: Female

Ages: 70 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Females
• 70-80 years
• Living in the community

Exclusion criteria

• Renal disease
• Diseases that contraindicate vitamin D supplementation
• Medications affecting bone
• Malignancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

1

Active Comparator group

Treatment:

Dietary Supplement: vitamin D twice daily

2

Experimental group

Treatment:

Dietary Supplement: Vitamin D3 oil three times in a year