Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering

University of Michigan

Status: Begins enrollment this month

Conditions: Stuttering, Adult; Stuttering; Stutter; Stuttering, Developmental

Treatments: Behavioral: Speech Production During functional magnetic resonance imaging (MRI)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT07180628

1R01DC022763-01 (U.S. NIH Grant/Contract)

HUM00269390

Details and patient eligibility

About

The overall objective of this study is to examine inter effector areas (IEAs) activity and functional connectivity during continuous speech production in stuttering adults.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Are between the ages of 18-65 years
• Have otherwise normal speech, language, hearing and cognition
• Speak English as their primary language
• Currently stutter

Exclusion criteria

• Have serious medical or neurological conditions (e.g., stroke, traumatic brain injury, Parkinson's disease, etc.)
• Have had a closed head injury (e.g., concussion)
• Have a reading disorder (e.g., dyslexia)
• Have hearing loss
• Have metal or electronic implants (e.g., cochlear implants, pacemakers, etc.)
• Are currently pregnant

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Stutter group

Experimental group

Description:

Participants that stutter

Treatment:

Behavioral: Speech Production During functional magnetic resonance imaging (MRI)