Organization in Acute Atrial Fibrillation Post Open Heart Surgery (A-Fib)

State University of New York - Upstate Medical University

Status: Completed

Conditions: Atrial Fibrillation

Study type: Observational

Funder types: Other

Identifiers

NCT00614107

5301UMU

Details and patient eligibility

About

A form of irregular heart rate called, Atrial Fibrillation (AF) is a major clinical problem. It afflicts about 2 million Americans and is the single largest heart related cause of stroke. However, despite 120 years of speculation and research, the mechanisms that cause AF are poorly understood. Acute AF is also the most common irregular heart rate after open-heart surgery in patients. This is seen in as many as 30% of such patients and often results in a longer hospital stay.

In this study we would like to study the pattern of atrial fibrosis (scar tissue in the heart) and an associated blood marker (a protein called pro-collagen-1) in those patients concurrently having open heart surgery.

Enrollment: 75 patients

Sex: All

Ages: 18 to 79 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. 18 years of age, Male or Female
2. Able to provide consent
3. Cardiac surgery, CABG of Valve replacement or repair.

Exclusion criteria

1. If AF terminates within 1 hour of initiation.
2. If the patient undergoes electrical cardioversion and/or receives digitalis within the first hour of inclusion.
3. If the patients and/or their family or the primary caregiver choose to be excluded from the study anytime, even after the initial 24-hour period.
4. If the patient expires within 1 hour of inclusion into the study. -