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ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence

National Institutes of Health (NIH) logo

National Institutes of Health (NIH)

Status

Completed

Conditions

Diabetes
Urinary Incontinence

Study type

Observational

Funder types

Other
NIH

Identifiers

NCT00069368
P50DK064538 (U.S. NIH Grant/Contract)
ORSCOR dk64538 (completed)

Details and patient eligibility

About

This study consists of two studies with overlapping cohorts. One is a follow up epidemiological study of urinary incontinence, the other is a case control study of lower urinary tract dysfunction in women with diabetes.

Study One:

Subjects for the study will be a retrospective cohort of 2100 middle-aged and older women from a large health maintenance organization who have participated in the Reproductive Risk Factor for Incontinence Study at Kaiser (RRISK). The RRISK I study assembled a retrospective cohort of long-term female Kaiser Permanente members to determine the association between specific childbirth events, hysterectomy, hormone use and urinary incontinence later in life. The study also provides descriptive information on urinary incontinence by type, age, ethnicity, severity and age of onset.

Study Two:

Women with diabetes have a 30-70% increased risk of lower urinary tract dysfunction, including lower urinary tract symptoms, urinary incontinence, and ultimately bladder cystopathy. This sudy investigates the natural history, risk factors, and possible mechanisms of lower urinary tract dysfunction and infection among women with type 2 diabetes as compared to women without diabetes.

Enrollment

2,161 patients

Sex

Female

Ages

44 to 73 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Previous participation in the Reproductive Risk Factors for Incontinence Study at Kaiser.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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