ClinicalTrials.Veeva

Menu

OS NMB Depth Measured by Central and Peripheral Monitor.

A

AZ Sint-Jan AV

Status

Unknown

Conditions

Neuromuscular Blockade

Treatments

Diagnostic Test: measuring neuromuscular block

Study type

Observational

Funder types

Other

Identifiers

NCT03660891
OS NMBcentralperipheral

Details and patient eligibility

About

Comparing during anesthesia in the same patient 2 neuromuscular monitors on the same arm.

Full description

NMT (neuromuscular transmission) depth can be measured at the same arm with two different methods during clinical practice.

the first (TOF Watch) measures the musculus adductor pollicis acceleration while the second method (TOF Cuff Monitor) uses a blood pressure cuff to measure the pressure changes induced by the upper arm muscles.

During general anesthesia when NMB (neuromuscular block) is required both methods are used. Every 5 minutes, if clinical required, the NMB is monitored by TOF-PTC. If the measurement of TOF is zero the monitor continues by measuring PTC ( the system will measure TOF followed by PTC if TOF is zero) TOF-PTC is recorded and later compared for identity or systematic difference in one or the other direction.

The measured answer can be TOF 4 (4 answers) with a ratio between answer 1 and 4 expressed and a percentage, TOF 3 (3 answers), TOF 2, TOF 1, TOF 0 + PTC 20, TOF 0 + PTC 19, up to TOF 0 + PTC 0

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: all patients scheduled for an elective surgery requiring neuromuscular block during anesthesia

  • laparoscopic surgery of upper abdomen including all types of bariatric surgery.

Exclusion Criteria: not possible to measure NMT (neuromuscular transmission) by cuff or thumb monitor

  • upper arm obesity excluding the use of an upper arm blood pressure cuff
  • allergy to NMB (neuromuscular blockers)
  • contra indication for a deep NMB

Trial contacts and locations

1

Loading...

Central trial contact

Jan Paul Mulier, PhD; Kris Leleu, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems