Osteoarthritis Relationships and Tobacco " Ancillary Study Khoala "

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Osteoarthrosis

Study type: Observational

Funder types: Other

Identifiers

NCT02910830

13-PP-04

Details and patient eligibility

About

The role of tobacco in osteoarthritis remains controversial. The Khoala cohort is the first multicenter French cohort of subjects with knee and / or hip osteoarthritis prevalent . It guarantees its methodology great representativeness and therefore an interesting material for the study of risk factors in the population. In addition, it should have little here Radiographs of hands for all its patients. It therefore has the opportunity to study a possible relationship between tobacco and hip osteoarthritis , knee and hand but also to study the relationship between tobacco and structural evolution of hip osteoarthritis and / or symptomatic knee.

Enrollment: 848 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men or women aged between 40 and 75 years
• hip osteoarthritis and / or knee ( stifle ) , unilateral or bilateral , symptomatic with a confirmed diagnosis and meeting the ACR criteria , representative of prevalent cases in France during the constitution of the cohort
• Affiliation to social security

Exclusion criteria

• Presence of a hip or knee prosthesis of the painful joint at baseline ;
• Antecedent osteotomy ;
• severe comorbidity likely to affect significantly the quality of life or induce a major healthcare consumption regardless of osteoarthritis ;
• Knee pain with patellofemoral osteoarthritis isolated , that is to say without tibiofemoral osteoarthritis associated ;
• Other pathologies of these joints
• adults subject to a legal protection measure or unable to express their opposition not to participate in the study