Osteopathy and Latent Hypothyroidism

Emanuel Amier Diekmann

Status: Unknown

Conditions: Latent Hypothyroidism

Treatments: Other: OMT

Study type: Interventional

Identifiers

NCT02430857

17-5-2015

Details and patient eligibility

About

This study evaluates the effectiveness of stimulating the neurological segments c8-th5 in patients with latent hypothyroidism.

One half of the participants will receive an osteopathic manuel treatment in order to stimulate the relevant segments, the other half will receive no treatment.

Full description

Patients with latent hypothyroidism show an increased hormone status in TSH and a normal hormone status in fT4. A study has shown that osteopathic treatment had positive effects to some symptoms in patients with latent hypothyroidism. The study was using the pain inventory as the instrument to measure the effect. In this study we want to evaluate the effectiveness of the treatment on the hormone status (TSH, fT4) The intervention group will receive a neurological osteopathic stimulation over 5 weeks. A parallel control group will not receive any therapy.

A follow up blood screening (TSH, fT4) will be done. The results of both groups will be compared.

Enrollment: 40 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• latent hypothyroidism

Exclusion criteria

• Factors that Alter Thyroxine and Triiodothyronine Binding in Serum
• Increased thyroxin-binding globulin
• Decreased thyroxin-binding globulin
• Binding inhibitors
• Inherited Salicylates
• Pregnancy
• Androgens
• Furosemide
• Neonatal state
• Anabolic steroids
• Free fatty acids
• Estrogens
• Glucocorticoids
• Phenytoin
• Hepatitis
• Severe illness
• Carbamazepine
• Porphyria
• Hepatic failure
• nonsteroidal antiinflammatory drug (variable, transient)
• Heroin
• Nephrosis
• Heparin
• Methadone
• Nicotinic acid
• Mitotane L-Asparaginase
• 5-Fluorouracil
• SERMS (e.g., tamoxifen, raloxifene)
• Perphenazine
• spinal pathologies

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

OMT-Group

Experimental group

Description:

The OMT-group will get an osteopathic treatment once a week for 1 hour for 5 weeks. The blood will be screened again after the treatment.

Treatment:

Other: OMT

Controll Group

No Intervention group

Description:

This group will receive no treatment. A blood screening is made again after 5 weeks.