Osteoprotegerin Before and After Periodontal Surgery

Cairo University (CU)

Status: Completed

Conditions: Chronic Periodontitis

Treatments: Procedure: Open flap debridement

Study type: Interventional

Funder types: Other

Identifiers

NCT02160613

OPG_OFD

Details and patient eligibility

About

The study hypothesis:

Is Osteoprotegerin a diagnostic and/or prognostic marker of periodontal disease?

Full description

assessment of osteoprotegerin in patients with chronic periodontitis before and after periodontal surgery in gingival crevicular fluid, saliva and gingival tissues.

Enrollment: 30 patients

Sex: All

Ages: 32 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• severe chronic periodontitis, having pocket depth of ≥ 5 mm and clinical attachment level ≥ 5 mm

Exclusion criteria

• pregnant women
• subjects had <22 permanent teeth
• having any given systemic disease
• taking any type of medication and/or antibiotic therapy during the 3 months before the study
• received periodontal treatment within the past 12 months
• current or former smokers.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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30 participants in 1 patient group

Open flap for periodontitis patients

Other group

Description:

Open flap debridement

Treatment:

Procedure: Open flap debridement