Otoacoustic Emissions in Different Blood Types

Istanbul University - Cerrahpasa (IUC)

Status: Completed

Conditions: Hearing Loss, Cochlear

Treatments: Diagnostic Test: Otoacoustic emissions (non-invasive)

Study type: Observational

Funder types: Other

Identifiers

NCT06326866

E-74555795-050.04-941208

Details and patient eligibility

About

The objective of this study is to examine whether ABO and Rhesus (Rh) blood group systems have an association with distortion product otoacoustic emission (DPOAE) and transient otoacoustic emission (TEOAE) amplitudes with the hypothesis of blood groups may affect hearing thresholds.

Full description

Many factors have a significant impact on otoacoustic emission (OAE) measurement and quality of analysis. Race, age and gender are among the non-pathological factors. To date there is clear data to demonstrate the association of blood types with OAEs. The aim of our research is to investigate the relation of different blood groups (ABO) and Rh factors on transient evoked OAE and distortion product OAE amplitudes and inner ear potentials, differences between ears and to contribute to the limited literature on cochlear hearing loss susceptibility and blood groups with the hypothesis that blood groups may be associated with hearing thresholds.

Enrollment: 70 patients

Sex: All

Ages: 18 to 26 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• not having hearing loss
• having a blood group card obtained from health institutions

Exclusion criteria

• not meeting inclusion criteria

Trial design

70 participants in 8 patient groups

Individuals with A Rh (+) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as A Rh (+) will be included and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with A Rh (-) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as A Rh (-) will be included and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with B Rh (+) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as B Rh (+) will be included and and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with B Rh (-) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as B Rh (-) will be included and and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with AB Rh (+) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as AB Rh (+) will be included and and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with AB Rh (-) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as AB Rh (-) will be included and and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with O Rh (+) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as O Rh (+) will be included and and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)

Individuals with O Rh (-) blood group

Description:

Individuals with normal hearing and whose blood group was previously determined as O Rh (-) will be included and and Transient evoked Otoacoustic Emissions (TOAE) and Distortion Product Otoacoustic Emissions (DPOAE) will be performed.

Treatment:

Diagnostic Test: Otoacoustic emissions (non-invasive)