Outcome After Avascular Necrosis of the Femoral Head in Young Patients (AVN)

University Hospital Basel

Status: Withdrawn

Conditions: Avascular Necrosis of the Femoral Head

Treatments: Other: questionnaire for course of the disease; Other: questionnaires for patient reported outcome

Study type: Observational

Funder types: Other

Identifiers

NCT03753282

2018-01264 ch18Saxer3;

Details and patient eligibility

About

1. The course of AVN between Initial diagnosis and total hip replacement (THA) is analysed. The impact of early interventions versus conservative therapy in AVN before THA will be evaluated.
2. The short and long term outcomes of AVN patients undergoing THA with respect to complications, reoperations and quality of life are investigated. Potential risk factors for adverse outcomes will be investigated.

Full description

The study is to describe the course of avascular necrosis (AVN) of the femoral head from initial diagnosis and to collect data on treatment options and the further course in these cases. The duration from initial diagnosis of AVN to joint replacement as total hip arthroplasty (THA) will be analysed and the course after joint replacement with potential short- and long-term complications will be evaluated.

The impact of THA after AVN on activities of daily living will be assessed by Euroquol 5 Dimensions (EQ-5D-5L) and Hip disability and Osteoarthritis Outcome Score (HOOS) questionnaires.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• MRI of the hip available from diagnosis at the USB or KSBL Liestal
• Informed Consent

Exclusion criteria

• Insufficient knowledge of project languages (English, German, French)

Trial design

0 participants in 2 patient groups

Population 1

Description:

Patients with a first AVN-related contact (initial or confirmed diagnosis) at the Universitätsspital Basel (USB) or Kantonsspital Basel-Liestal (KSBL) in the years between 1999-2006 (being assessed by questionnaires for patient reported outcome and questionnaire for course of the disease)

Treatment:

Other: questionnaire for course of the disease

Other: questionnaires for patient reported outcome

Population 2

Description:

Patients with a THA because of AVN in the years 2000-2007 (being assessed by questionnaires for patient reported outcome and questionnaire for course of the disease)

Treatment:

Other: questionnaire for course of the disease

Other: questionnaires for patient reported outcome