Outcome of Carbon Dioxide Versus Air Insufflations During Endoscopic Retrograde Cholangiopancreatography (ERCP)

Asian Institute of Gastroenterology, India

Status: Completed

Conditions: Obstructive Jaundice

Study type: Observational

Funder types: Other

Identifiers

NCT01321203

AIG-GI2010-02

Details and patient eligibility

About

To assess the safety and efficacy of CO2 insufflations during ERCP

1. Primary objective:

   To assess the patient's symptoms, abdominal pain and abdominal distension post procedure (ERCP) in the study group.

2. Secondary objective:

Endoscopist:

• To assess the adequacy of bowel distension for adequate luminal visualization
• To assess the peristaltic movement during the ERCP

Anesthetist:

• To measure the PCO2 level in patient post procedure.
• To assess the amount of sedation required during the procedure.
• To assess saturation and vital signs through out the procedure.
• To assess requirement of buscopan.

Full description

mentioned in complete

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All consecutive adult patients referred for ERCP to AIG Hyderabad

Exclusion criteria

• Age < 18 years old excluded from the study.
• Patients with COPD.
• Patients with poor ejection fractions and decompensated heart failure.
• Patients with acute illness that require emergency ERCP and not fit for pre procedure and post procedure assessments.
• Patients with recent endoscopic procedure within 24 hours.
• Patient with history of recent surgery within 7 days of duration.
• Pregnant patients.
• Patients not keen to give consent for the study.

Trial design

500 participants in 2 patient groups

Group-A, use of air;

Group-B use of CO2