Outcome of Cardiac Arrest Patients Following Guidelines Implementation Over the Years (IMPACT-ACC)

Mauro Panigada

Status: Enrolling

Conditions: Cardiac Arrest

Study type: Observational

Funder types: Other

Identifiers

NCT06608771

5033

Details and patient eligibility

About

The study aims to evaluate the level of local implementation of the new interventions introduced by the guidelines for post-cardiac arrest management and their impact on the survival of patients resuscitated from cardiac arrest and admitted to intensive care over a 14-year period. During this time period, the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) introduced three new guidelines for post-cardiac arrest management, each five years apart: the 2010, 2015, and 2021 guidelines.

Full description

This study is a retrospective multicenter cohort observational study (two centers involved: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Fondazione IRCCS San Gerardo dei Tintori).

All patients admitted to the Intensive Care Units (ICU) of the hospitals involved in the study from January 1, 2011, to May 30, 2024, following cardiac arrest of any etiology, who meet the inclusion and exclusion criteria, will be enrolled.

Enrollment: 693 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients resuscitated from cardiac arrest and admitted to intensive care unit
• Age ≥ 18 years
• Out-of-hospital and in-hospital cardiac arrest
• Cardiac arrest of any etiology

Exclusion criteria

• Pediatric patients (<18 years)
• Patients not admitted to one of the aforementioned intensive care units.

Trial design

693 participants in 1 patient group

Out-of-hospital cardiac arrest (OHCA) and In-hospital cardiac arrest (IHCA) patients

Description:

The study population includes all adult patients resuscitated from cardiac arrest and subsequently admitted to the Intensive Care Unit over a 14-year-period