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Outcome of Cataract Surgery With Uveitis

A

Assiut University

Status

Unknown

Conditions

Cataract; Complicata

Treatments

Procedure: cataract surgery

Study type

Interventional

Funder types

Other

Identifiers

NCT04333069
cat in uveitic patients

Details and patient eligibility

About

Aim of the study is to evaluate outcome of cataract surgery in different types of uveitis as regarding best corrected visual acuity (BCVA) and rate of post operative complications.

Full description

Cataract is the main cause of reversible blindness in patients with uveitis. Cataract occurs in up to 50% to 70% of patients with uveitis.

Preoperative complications, including anterior synechiae, posterior synechiae, and pupillary membrane formation, may increase surgical challenges. In addition, recurrent inflammation increases the incidence of postoperative complications and often affects the visual prognosis. In recent years, phacoemulsification with intra ocular lens (IOL)implantation has become the main surgical method for treating uveitis (complicated cataract), and the visual prognosis of patients who undergo this procedure is usually favorable.

Surgical treatment may be effective but is associated with higher rates of complication than in non uveitic eyes. Cystoid macular edema (CME) is the most common complication cataract surgery in the general population. Although, in most cases, the macular edema is self-limited, in rare cases it can lead to long-term visual deterioration that is difficult to treat.

Another common complication after cataract surgery is posterior capsule opacification (PCO) , leading to symptoms of glare or blurred vision, reduced visual acuity, or impaired posterior segment exam. Factors that are critical in the development of PCO include surgical technique, type of implanted intra ocular lens (IOL) either foldable hydrophilic acrylic, hydrophobic acrylic or silicone and postoperative control of uveitis

Enrollment

50 estimated patients

Sex

All

Ages

16 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Visually significant cataract ( means opacification of the crystalline lens adequate to interfere with vision)in patients with uveitis controlled for at least 1month.

Exclusion criteria

  • Irreversible pathology affecting outcome e.g. macular scar ,optic atrophy, and retinal detachment.
  • Patients with active uveitis (means inflammation inside the eye).
  • Patients less than 16 years old.

Trial design

Primary purpose

Screening

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

50 participants in 1 patient group

Uncorrected and best corrected visual acuity
Other group
Description:
Measuring of uncorrected and best corrected visual acuity after phaco emulsification and irrigation aspiration cataract surgery
Treatment:
Procedure: cataract surgery

Trial contacts and locations

0

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Central trial contact

Mona Abdallah Abd AlRazik Ahmed, MD; Mohammed Gamal Saleh, lecturer

Data sourced from clinicaltrials.gov

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