Outcome of Different IOLs in Patients With and Without Uveitis

Vastra Gotaland Region

Status: Completed

Conditions: Inflammation; Uveitis; Cataract; Posterior Capsule Opacification

Treatments: Device: Hydrophobic IOL: Vivinex (HOYA); Device: Hydrophilic IOL: INCISE (Bausch+Lomb)

Study type: Interventional

Funder types: Other

Identifiers

NCT02975895

031-16

Details and patient eligibility

About

Cataract, is a clouding of the lens in the eye gradually leading to reduction of the visual acuity. In most cases it can be managed with surgery, removing the own lens and replacing it with an artificial lens, intraocular lens (IOL). These lenses are made in different materials with different properties.

Uveitis refers to an inflammation in the iris, ciliary body and choroid. Patients with this disease have an increased risk of developing cataract due to the inflammation itself and treatment with steroids. They also have an increased risk of complications during surgery and postoperatively. In this group the selection of IOL might be of greater importance.

The aim of this prospective randomized controlled study is to compare the outcome of hydrophobic and hydrophilic intraocular lenses in patients with and without uveitis

Enrollment: 56 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cataract requiring surgery
• Ability to understand and sign consent form

Exclusion criteria

• Extensive corneal scarring
• Other eye surgery less than 3 months before inclusion
• Unregulated glaucoma
• Active uveitis (increased inflammation and treatment less than 3 months before inclusion)
• Intraoperative complications (capsular tear or vitreous loss)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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56 participants in 2 patient groups

Hydrophobic IOL: Vivinex (HOYA)

Other group

Description:

Intraocular lens with hydrophobic properties: Vivinex (HOYA).

Treatment:

Device: Hydrophobic IOL: Vivinex (HOYA)

Hydrophilic IOL: INCISE (Bausch+Lomb)

Other group

Description:

Intraocular lens with hydrophilic properties: INCISE (Bausch+Lomb).

Treatment:

Device: Hydrophilic IOL: INCISE (Bausch+Lomb)