Outcome of Embryo Culture at Two Oxygen Tensions

University Medical Centre Maribor

Status: Completed

Conditions: Embryo Development

Treatments: Other: oxygen concentration in the culture atmosphere

Study type: Interventional

Funder types: Other

Identifiers

NCT00718822

P3-0327

Details and patient eligibility

About

The purpose of this study is to assess whether reduced oxygen tension in embryo culture has any effect on clinical outcome.

Enrollment: 647 patients

Sex: Female

Ages: 22 to 44 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• stimulated Intra Cytoplasmic Sperm Injection (ICSI) cycle

Exclusion criteria

• less than one mature (metaphase II) oocyte at the time of denudation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

647 participants in 2 patient groups

I

Experimental group

Description:

5% oxygen concentration in the culture atmosphere

Treatment:

Other: oxygen concentration in the culture atmosphere

II

Experimental group

Description:

20% oxygen concentration in the culture atmosphere

Treatment:

Other: oxygen concentration in the culture atmosphere