Outcome of LA Versus GA for Staged CEA Prior To CABG

Thomas Aherne

Status: Completed

Conditions: Coronary Artery Disease; Stroke; Carotid Artery Diseases

Treatments: Procedure: Carotid endarterectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04901000

University Hospital Birmingham

Details and patient eligibility

About

A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months.

The rate of postoperative stroke and complications was compared between CEA performed under Local anaesthetic (LA) to those performed under General anaesthetic (GA).

Full description

The primary outcome was the rate of postoperative stroke in patients that had staged CEA prior to CABG. This was defined as CEA within a period of 4 weeks prior to CABG.

We retrospectively looked at those patients that fulfilled the inclusion criteria and had CEA performed either under LA (Group A) or under GA (Group B). We measured the 30 days' postoperative stroke rate as the main outcome. We also looked at the rate of intraoperative stroke.

Additionally, we assessed the rate for developing nerve injuries and/or hematoma postoperatively. Finally, we examined the risk for developing postoperative stroke in patients with bilateral significant carotid artery disease that underwent surgery in one side.

Enrollment: 44 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients that had carotid endarterectomy performed in staged fashion within 6 months before a CABG operation.

Exclusion criteria

• Patients diagnosed with symptomatic carotid disease

Trial design

44 participants in 2 patient groups

Carotid Endarterectomy under Local Anaesthetic Pre-CABG

Description:

Patients that underwent carotid endarterectomy under local anaesthetic prior to coronary artery bypass operations in staged fashion within 6 months.

Treatment:

Procedure: Carotid endarterectomy

Carotid Endarterectomy under General Anaesthetic Pre-CABG

Description:

Patients that underwent carotid endarterectomy under general anaesthetic prior to coronary artery bypass operations in staged fashion within 6 months.

Treatment:

Procedure: Carotid endarterectomy