Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease

Benha University

Status and phase: Completed; Phase 4

Conditions: Ocular Surface Disease

Treatments: Drug: Omega 3; Device: punctal plug

Study type: Interventional

Funder types: Other

Identifiers

NCT03686059

hamaky1

Details and patient eligibility

About

Ocular surface disease is a common adverse effect of systemic isotretinoin therapy.

The investigators consider that punctal plugs and Omega 3 is a good line for treatment of ocular surface disease associated with systemic isotretinoin therapy

Full description

Subjective and objective evaluation of ocular surface disease was done at baseline ,1 and 3 months of the study .

Enrollment: 90 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• systemic isotretinoin therapy

Exclusion criteria

• systemic or ocular diseases ,previous ocular surgery, corneal pathology and contact lens wearer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 3 patient groups

punctal plug

Experimental group

Description:

SOFT PLUG® Preloaded Silicone Plugs by OASIS®

Treatment:

Device: punctal plug

Combined

Experimental group

Description:

SOFT PLUG® Preloaded Silicone Plugs by OASIS® plus Daily intake of DHA (docosahexaenoic acid)

Treatment:

Device: punctal plug

Drug: Omega 3

control

No Intervention group

Description:

no medication was given