Outcomes of Intrathecal Analgesia in Colorectal Surgery

Mayo Clinic

Status: Completed

Conditions: Surgery

Treatments: Drug: Hydromorphone Hydrochloride

Study type: Observational

Funder types: Other

Identifiers

NCT03411109

13-007936

Details and patient eligibility

About

Multimodal analgesia, sometimes including intrathecal analgesia (IA), is essential in any enhanced recovery pathway (ERP). This study aimed to evaluate the safety, feasibility, and optimal IA regimen in colorectal surgical patients.

Enrollment: 601 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All adult colorectal patients from October 2012 through December 2013 in which patients received single-injection IA as part of a multimodal analgesic strategy for ERP.
• Undergoing an elective colorectal operation (minimally invasive or open)

Exclusion criteria

• Patients aged < 18 years
• American Society of Anesthesiologists (ASA) 5 and 6 classification
• pregnancy
• failure to provide research authorization.
• emergent operations

Trial design

601 participants in 2 patient groups

Opioid Only Intrathecal

Treatment:

Drug: Hydromorphone Hydrochloride

Opioid + Local Anesthetic Intrathecal

Treatment:

Drug: Hydromorphone Hydrochloride