Outcomes of Neoadjuvant Therapy for Rectal Cancer in a Tertiary Asian Institute

Singapore Health Services (SingHealth)

Status: Completed

Conditions: Oncology; Rectal Cancer

Treatments: Radiation: neoadjuvant long course chemoradiotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT05607186

2019/2342

Details and patient eligibility

About

This is a retrospective cohort study that aims to evaluate the correlation of magnetic resonance tumour regression grade (mrTRG) and pathological TRG (pTRG) of locally advanced rectal cancer after neoadjuvant long course chemoradiotherapy as well as the prognostic value of mrTRG on survival.

Enrollment: 59 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Rectal cancer
• At least 1 high risk feature on MRI
• Undergo long course neoadjuvant chemoradiotherapy (LCCRT)

Exclusion criteria

• metastatic disease
• Patients who undergo short course radiotherapy
• Patients without a repeat MRI after completion of LCCRT