Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection

Central Hospital, Nancy, France

Status: Active, not recruiting

Conditions: Perforation Colon; Colorectal Neoplasms; Perforation of Rectum

Treatments: Procedure: Endoscopic submucosal dissection

Study type: Observational

Funder types: Other

Identifiers

NCT05728710

2022PI178

Details and patient eligibility

About

Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for all lesions. Endoscopic submucosal dissection (ESD) allows en bloc resection of large superficial colorectal neoplasms, increasing curative resection rate and decreasing local recurrence risk. However, the risk of perprocedural or delayed perforation is higher compared to wild field piece meal endoscopic mucosal resection. Endoscoping clipping and closing methods mostly allow conservative treatment, but some case still necessitate surgery. The aim of our study is to describe and ananalyse outcomes after perprocedural or delayed perforation in all patients undergoing ESD and analyse the need for surgical intervention.

Enrollment: 350 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients from the FECCO (NCT04592003) cohort experiencing perprocedural or delayed perforation
• age over 18 years old

Exclusion criteria

• patients refusing exploitations of health datas
• patient treated with endoscopic mucosal resection

Trial design

350 participants in 1 patient group

Perforation

Description:

all patients with immediate or delayed perforation identified from the FECCO (NCT04592003)

Treatment:

Procedure: Endoscopic submucosal dissection