Outcomes of Posterior Urethral Valve Fulguration

Assiut University

Status: Not yet enrolling

Conditions: Posterior Urethral Valve

Treatments: Procedure: Fulguration

Study type: Observational

Funder types: Other

Identifiers

NCT06867263

Posterior urthral valve

Details and patient eligibility

About

To evaluate the long-term outcome after fulguration of the posterior urethral valve.

Full description

Posterior Urethral Valves (PUV) are the most common cause of lower urinary tract obstruction. More severe forms are detected early in pregnancy (mainly type I), while other forms are usually discovered later in childhood when investigating lower urinary tract symptoms. Bladder dysfunction is common and is associated with urinary incontinence in about 55% (0%-72%). Despite the removal of the obstruction by urethral valve ablation, pathological changes in the urinary tract can occur with progressive bladder dysfunction, which can cause deterioration of the upper urinary tract as well. For this reason, all children with PUV require long-term follow-up, always until puberty. In many cases, the life-long current status is uncertain. The current literature lacks research on long-term outcomes.

Enrollment: 35 estimated patients

Sex: Male

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with fulguration of PUV since 1 year or more

Exclusion criteria

• Patients with neurogenic bladder or meningocele or spina bifida .

Patients with renal parenchymal disease and inflammation not related to posterior urethral valve .

Diabetic patients .

Parental refusal .