Outcomes of Smoker and Drinker With Esophageal Squamous Cell Carcinoma After Esophagectomy (OSinEC)

U

University of Electronic Science and Technology of China (UESTC)

Status

Enrolling

Conditions

Outcomes of Smoker and Drinker After Esophagectomy

Treatments

Other: No intervention

Study type

Observational

Funder types

Other

Identifiers

NCT06269341
SCCH-TS2208

Details and patient eligibility

About

Our study demonstrates that patients who did not consume alcohol or smoke had a significant advantage in overall survival (OS) after undergoing esophagectomy. Furthermore, our findings indicate that there was no statistically significant difference in OS between patients with a history of both smoking and drinking, and those who only smoked or drank

Enrollment

2,957 estimated patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients with esophageal cancer

Exclusion criteria

(1) pathology confirmed a non-squamous cell carcinoma, (2) the tumor was located outside of the thoracic region, (3) R1/R2 resection was performed indicating incomplete tumor removal, (4) evidence of distant tumor metastasis was observed, (5) they underwent preoperative neoadjuvant therapy, (6) pTis/T1a stage (7) Missing data.

Trial design

2,957 participants in 2 patient groups

high-risk
Description:
Smoker and Drinker with Esophageal Squamous Cell Carcinoma after Esophagectomy
Treatment:
Other: No intervention
low-risk
Description:
Non-Smoker and Non-Drinker with Esophageal Squamous Cell Carcinoma after Esophagectomy

Trial contacts and locations

1

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Central trial contact

Xuefeng Leng; Lin Peng

Data sourced from clinicaltrials.gov

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