Outcomes of Smoker and Drinker With Esophageal Squamous Cell Carcinoma After Esophagectomy (OSinEC)

University of Electronic Science and Technology of China (UESTC)

Status: Enrolling

Conditions: Outcomes of Smoker and Drinker After Esophagectomy

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06269341

SCCH-TS2208

Details and patient eligibility

About

Our study demonstrates that patients who did not consume alcohol or smoke had a significant advantage in overall survival (OS) after undergoing esophagectomy. Furthermore, our findings indicate that there was no statistically significant difference in OS between patients with a history of both smoking and drinking, and those who only smoked or drank

Enrollment: 2,957 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

patients with esophageal cancer

Exclusion criteria

(1) pathology confirmed a non-squamous cell carcinoma, (2) the tumor was located outside of the thoracic region, (3) R1/R2 resection was performed indicating incomplete tumor removal, (4) evidence of distant tumor metastasis was observed, (5) they underwent preoperative neoadjuvant therapy, (6) pTis/T1a stage (7) Missing data.

Trial design

2,957 participants in 2 patient groups

high-risk

Description:

Smoker and Drinker with Esophageal Squamous Cell Carcinoma after Esophagectomy

Treatment:

Other: No intervention

low-risk

Description:

Non-Smoker and Non-Drinker with Esophageal Squamous Cell Carcinoma after Esophagectomy