Outcomes of Surgery of Aortic Valve (Aortic Surgery)

Assiut University

Status: Unknown

Conditions: Aortic Valve Disease

Treatments: Procedure: Aortic valve replacement

Study type: Observational

Funder types: Other

Identifiers

NCT04277572

17200395

Details and patient eligibility

About

Overall Goal: To study the outcomes of patients undergoing aortic valve surgeries, different approaches such as standard aortic valve replacement, aortic valve repair, novel techniques as Ozaki's procedure and their subsequent results and complications.

• Objective 1: Identify predictors of complications following different types of aortic valve surgery accordingly.
• Objective 2: Determine the value of each type in terms of advantages and disadvantages.
• Objective3: Assess outcomes such as postoperative life expectancy, hospital stay, prognosis and quality of life.

Enrollment: 30 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with severe symptomatic aortic valve lesion.

2. Asymptomatic aortic insufficiency patients with left ventricular dysfunction or significant left ventricular dilatation (LV end diastolic diameter>70 mm or LV end systolic diameter>50 mm.

3. Patients with aortic regurgitation caused by:

   • a dilated aortic annulus
   • conjoined cusp prolapse in bicuspid aortic valves (BAV)
   • single cusp prolapse in tricuspid aortic valves
   • aortic valve cusp perforation from endocarditis

Exclusion criteria

• Patients with previous aortic root or valve surgery.

Trial design

30 participants in 1 patient group

Aortic valve replacement

Description:

using different ways of aortic valve replacement either by prosthetic valves or by ozaki technique

Treatment:

Procedure: Aortic valve replacement