Outcomes of the Embryos of Different Ovarian Follicle Sizes, and the miRNA Detection in Their Blastocyst Culture

Acibadem University

Status: Enrolling

Conditions: Embryo Quality

Treatments: Procedure: Oocyte pick-up

Study type: Observational

Funder types: Other

Identifiers

NCT05947526

2023-10/349

Details and patient eligibility

About

In this study, it is aimed to analyze the outcomes of embryos obtained from ovarian follicle with different sizes, and identify the microRNA expression in the spent media of the blastocysts cultures.

Full description

In this study, it is aimed to analyze the outcomes of embryos obtained from ovarian follicle with different sizes. By this way, we assume to predict which follicle is able to give the best blastocyst. After the blastocysts are obtained from the different sized follicles, blastocyst cultures are going to be studied for the up and down-regulations of microRNA, besides the correlation of embryo quality with miRNA expression in the spent media.

Enrollment: 55 estimated patients

Sex: Female

Ages: 20 to 38 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female patients aged between 20-38 who are planned to have IVF treatment
• On the day of trigger before the oocyte pick-up, patients having at least 5, and 14 at most follicles exceeding 11mm
• Patient having BMI below 30

Exclusion criteria

• PCO patients
• Patients having endometriosis
• Patients having male factor with severe oligoazoospermia

Trial design

55 participants in 1 patient group

Women referring to infertility clinic for IVF treatment

Description:

Women who were referred to infertility clinic with complaint of not having baby go through IVF treatment, and having oocyte pick-up procedure with different sizes of ovarian follicles

Treatment:

Procedure: Oocyte pick-up