Ovarian Cancer Hemoscope Trial

Scripps Translational Science Institute

Status: Active, not recruiting

Conditions: Ovarian Neoplasms

Study type: Observational

Funder types: Other

Identifiers

NCT02811224

15-6644

Details and patient eligibility

About

This is a prospective, gold standard observational trial designed to enroll consecutive, consenting ovarian cancer patients for the purpose of determining sensitivity of an assay that detects circulating tumor DNA. This observational pilot trial will also be used to examine the genetic variants/mutations present in the tumor tissue DNA.

Enrollment: 50 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Case Group

• Patients with ovarian cancer undergoing surgery (all stages)
• Over 18 years old

Control Group

• Patients with a benign gynecological condition undergoing surgery
• Over 18 years old

Exclusion criteria

• Previous cancer diagnosis (all)
• Radiation therapy before surgical treatment
• Bone marrow transplant
• Chemotherapy before surgical treatment
• Invasive procedure resulting in damage to tissue (e.g., surgery, biopsy, thermal ablation) in the 7 days prior to baseline (pre-surgical) blood collection

Trial design

50 participants in 2 patient groups

Ovarian Cancer

Benign Neoplasm