Ovarian Reserve and Embryo Implantation (IRO)

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: IVF; Ovarian Reserve

Treatments: Other: no intervention. observational study

Study type: Observational

Funder types: Other

Identifiers

NCT03989921

Local/2018/OP-01

Details and patient eligibility

About

Compare, in young patients with In vitro fertilization (IVF), the rate of embryo implantation by early culture transfer (J2-J3) between 2 groups of patients: "normo responders" vs. "poor responders".

Enrollment: 598 patients

Sex: Female

Ages: 35+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• IVF patient managed with or without ICSI between 01/01/2014 and 30/06/2015 in one of the two study centres
• Age < 35 years old
• Fresh transfer of at least one embryo between D2 and D6
• patients who have already received one or more transfer attempts.

Exclusion criteria

• No fresh transfer (Freeze All, segmentation failure, stimulation failure)
• Double successive embryo transfer (e. g. J3-J5). We did not retain these cases because if only one of the 2 embryos is implanted, it is not possible to know which transfer it corresponds to.
• Maternal serum FSH determination < 4 IU/ml at D3 in the baseline balance sheet (hypogonadotropic hypogonadism)

Trial design

598 participants in 2 patient groups

normo responders

Description:

that have an AMH dosage greater than or equal to 1.2 ng/mL

Treatment:

Other: no intervention. observational study

poor responders

Description:

with a dosage of less than 1.2 ng/mL

Treatment:

Other: no intervention. observational study