Ovarian Reserve Following Bilateral Salpingectomy Versus Tubal Ligation During Cesarean Section

Wolfson Medical Center (WMC)

Status: Unknown

Conditions: Ovarian Reserve

Treatments: Procedure: Tubal ligation; Procedure: Bilateral salpingectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT02377128

0028-15-WOMC

Details and patient eligibility

About

The aforementioned study was designed to evaluate short term ovarian reserve as assessed by anti-Mullerian hormone(AMH) levels following bilateral salpingectomy versus tubal ligation, as part of cesarean sections performed in women requesting future sterilization. The investigators aim to recruit 3 groups of 15 women undergoing elective cesarean section at the investigators' institution, 2 of which request sterilization (allocated to tubal ligation or bilateral salpingectomy) and one undergoing solely cesarean section. The groups will have blood drawn for AMH prior to the procedure and at a post-operation visit 8 weeks following. This is preformed in light of validated data offering better sterilization and possible diminished future risk of ovarian cancer with salpingectomy. Also, is has been proved to be just as safe as tubal ligation. This will be performed as a randomized controlled trial.

Enrollment: 45 estimated patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women undergoing elective cesrean section at the investigators' institution, requesting sterilization, willing to have blood withdrawn for AMH levels prior to surgery, willing to participate in 8 weeks post-operation follow up with blood withdrawn

Exclusion criteria

• Non-elective cesarean section, non willing to have blood withdrawn or participate in follow up, prior salpingectomy, prior premature ovarian failure/egg donation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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45 participants in 3 patient groups

Bilateral salpingectomy

Experimental group

Description:

Cesarean section with bilateral salpingectomy

Treatment:

Procedure: Bilateral salpingectomy

Tubal ligation

Active Comparator group

Description:

Cesarean section with tubal ligation

Treatment:

Procedure: Tubal ligation

No intervention

No Intervention group

Description:

Cesarean section with no additional intervention